COMPUTER CONTROLLED INFUSION OF PROPOFOL

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Science vs supposition: the case of target-controlled propofol infusion.

Editor—I continue to be confounded by the use of target-controlled propofol infusion (TCI) dosing paradigm as an accepted basis for presenting the scientific study in anaesthesia journals without specific documentation of instantaneous and total dose infusion rates, in conjunction with body weight and duration of infusion at the study point. Although TCI may be utilitarian in the clinical admin...

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Alternating asystole and atrial fibrillation after infusion of propofol and remifentanil with target-controlled infusion

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Propofol infusion syndrome.

The clinical features of propofol infusion syndrome (PRIS) are acute refractory bradycardia leading to asystole, in the presence of one or more of the following: metabolic acidosis (base deficit > 10 mmol.l(-1)), rhabdomyolysis, hyperlipidaemia, and enlarged or fatty liver. There is an association between PRIS and propofol infusions at doses higher than 4 mg.kg(-1).h(-1) for greater than 48 h d...

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A comparison of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion for oocyte retrieval

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 1989

ISSN: 0007-0912

DOI: 10.1093/bja/62.1.46